Using artificial intelligence to discover therapeutic antibodies

Former EMBL staff scientist founds a start-up – DenovAI – for broader, faster and cheaper antibody discovery using advanced machine learning and computational biophysics Antibodies are an important tool in the human immune system’s arsenal against disease. They attach to Mehr

EMBL Research News: International study proposes stool analysis for early detection of pancreatic cancer

Pancreatic cancer is one of the most lethal cancers due to its early local extension and metastatic behaviour. Some of the reasons for this high fatality rate are late diagnosis of the disease, especially since symptoms are unspecific and appear Mehr

EMBL-Research: The impact of drugs on gut microbes is greater than we thought

We are one of the most medicated generations of humans to live on our planet. Cardiometabolic diseases like type 2 diabetes, obesity, and coronary artery disease continue to increase in prevalence and together constitute the highest cause of mortality worldwide. Mehr

Structural biology reveals new opportunities to combat tuberculosis

Tuberculosis is one of the top ten causes of death worldwide, infecting about one-quarter of the world’s population. Although it is treatable, the rise of multidrug-resistant tuberculosis poses a major threat to global health security, and has been declared by Mehr

Wissenschaftler identifizieren synthetische Mini-Antikörper zur Bekämpfung von COVID-19

Lama-Mini-Antikörper und ihre synthetischen Imitationen Die Fähigkeit von SARS-CoV-2, Zellen zu infizieren, hängt von den Wechselwirkungen zwischen dem viralen Spike-Protein und dem menschlichen Zelloberflächenprotein ACE2 ab. Damit sich das Virus an der Zelloberfläche festhaken kann, bindet das Spike-Protein ACE2 über Mehr

Scientists identify synthetic mini-antibody to combat COVID-19

Llama mini-antibodies and their synthetic imitations The ability of SARS-CoV-2 to infect cells depends on interactions between the viral spike protein and the human cell surface protein ACE2. To enable the virus to hook onto the cell surface, the spike Mehr

How to remove unwanted components from the cell nucleus

An international team of scientists has uncovered how cells remove unwanted components from the nucleus following mitosis. The results, published in the journal Nature, stem from a fruitful collaboration between the European Molecular Biology Laboratory in Heidelberg and the Institute Mehr