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he debate on anesthetic effects in the developing brain has been stuck on mixed and often non-human data. FDA/NCTR used neural stem cell models and trusted VITROCELL SC3 Exposure Systems to keep xenon or desflurane, O₂, and CO₂ rock steady during Mehr
We put our VITROCELL Essentials Exposure Module to the test and ran a full internal uniformity study with diluted 1R6F reference cigarette smoke in both 12‑ and 24‑well formats – flows from 0.25 to 4 L/min. Spoiler: no drama, no Mehr
Our VITROCELL® 96 Exposure System has just been put through its paces in a new open‑access publication in Environmental Sciences Europe and it passed with flying colors. In this study, A549 cells at the air–liquid interface are exposed in a Mehr
As part of the ADVISAR project, the effects of emissions from aircraft turbines are being comprehensively investigated from a chemical and physical perspective. In collaboration between Zurich University of Applied Sciences and Adolphe Merkle Institute, human lung cell cultures are Mehr
First studies using our Cloud systems have already been successfully published (see link in the comments). Another widespread challenge is dry eye disease, where further studies are needed – and there’s a lot happening in the Eye-on-a-Chip community! For these Mehr
Vitrocell exposure systems enable direct air–liquid interface (ALI) exposure of mammalian cells and tissues to real-world airborne substances. From gases, complex mixtures, and combustion exhausts to cigarette smoke, e-cigarette vapor, household chemicals, nanomaterials, pharmaceutical aerosols, dry powders, and even viruses, Mehr
In traditional submerged cell culture, airway cells are covered by liquid – a condition that does not reflect how humans actually breathe. At the Air–Liquid Interface (ALI), mammalian cells and tissues are exposed directly to airborne substances, replicating human respiratory Mehr
Not all test atmospheres can be tested the same way. Some require the Continuous Flow Exposure Principle. In our Continuous Flow Exposure Systems, mammalian cells, tissues, and ex vivo material can be exposed to a constant flow of gases, complex Mehr
Following successful factory acceptance testing at Vitrocell in Waldkirch, we recently completed the final user training for the AirTox Monitor systems at LISA – Laboratoire Interuniversitaire des Systèmes Atmosphériques, (Université Paris Cité/Université Paris-Est Créteil (UPEC)/CNRS, France). What often matters most Mehr
In a recently published study, researchers from the Institut de Recherche Biomédical des Armées (IRBA) and INERIS carried out repeated, sub-lethal co-exposures to aluminum oxide nanoparticles (Al₂O₃ NPs) and hydrogen chloride (HCl). A human air–liquid interface co-culture model of alveolar Mehr